1,2-Pyrrolidinedicarboxylic acid, 5-oxo-, 2-(1,1-dimethylethyl)1-(phenylmethyl) ester, (S)- - Names and Identifiers
1,2-Pyrrolidinedicarboxylic acid, 5-oxo-, 2-(1,1-dimethylethyl)1-(phenylmethyl) ester, (S)- - Physico-chemical Properties
Molecular Formula | C17H21NO5
|
Molar Mass | 319.35234 |
Storage Condition | Sealed in dry,Room Temperature |
1,2-Pyrrolidinedicarboxylic acid, 5-oxo-, 2-(1,1-dimethylethyl)1-(phenylmethyl) ester, (S)- - Upstream Downstream Industry
1,2-Pyrrolidinedicarboxylic acid, 5-oxo-, 2-(1,1-dimethylethyl)1-(phenylmethyl) ester, (S)- - Introduction
Z-Pyr-OtBu(Z-Pyr-OtBu) is an organic compound whose chemical formula is C17H27NO4. Here are some important properties and information about Z-Pyr-OtBu:
Nature:
1. Appearance: The Z-Pyr-OtBu is a white crystalline solid.
2. Solubility: Soluble in common organic solvents such as methanol, ethanol and dimethylformamide.
Use:
1. Z-Pyr-OtBu is a commonly used protecting group (protecting group), which can be used to protect the amino (-NH2) functional group in amino acids. It can form a protecting group on the amino group to prevent unwanted reactions in certain organic synthesis processes.
2. Z-Pyr-OtBu can also be used for synthetic peptides and proteins and other complex molecules of organic chemistry.
Preparation Method:
The method of preparing Z-Pyr-OtBu includes the following steps:
1. First, N-benzyl-L-pyroglutamic acid is reacted with tert-butyl magnesium bromide (tBuMgBr) to produce tert-butyl ester of N-benzyl-L-pyroglutamic acid.
2. Then, the product obtained in the previous step is reacted with carbonyl diphenyl alkylene alcohol (PyrCOCl) to generate Z-Pyr-OtBu.
Safety Information:
1. Z-Pyr-OtBu are organic compounds and should be handled with care to avoid contact with skin, eyes and mucous membranes.
2. During operation and storage, good laboratory safety practices must be observed, such as wearing protective glasses, gloves and laboratory coats.
Last Update:2024-04-10 22:29:15